People
Dr.-Ing. Rohan Karande
Department of Solar Materials
Helmholtz Centre for Environmental Research
Building 9.1 (SIAB), Room 202
Permoserstraße 15
04318 Leipzig
Tel.: +49-341-235 46 83
Fax.: +49-341-235 45 12 86
E-Mail:
Research Interests
I am fascinated by nature`s designs as I believe similar principles can be used to solve numerous engineering issues. Nature`s solutions strongly motivates my research work for the application of miniaturization concepts for bioreactor development and their scale-up. I am currently working on developing a process idea based on a multistep reaction sequence using oxygenases to convert volatile, hydrophobic and toxic compounds. Additionally, I am part in a project developing efficient photobioreactors for the utilization of solar radiation and carbon dioxide for biomass generation and consequently biomaterial production.
CV / Scientific Career
| since 2014 | Scientist at the Department of Solar materials (SoMa), Helmholtz Centre for Environmental Research, Leipzig, Germany | ||
| 2012-2014 | Post-doctoral researcher at the Laboratory of Chemical Biotechnology, TU Dortmund University, Dortmund, Germany | ||
| 2007-2012 | Dissertation at the Laboratory of Chemical Biotechnology, TU Dortmund University, Dortmund, Germany |
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| 2004-2007 | Master of Science in Chemical Engineering (M. Sc.) with specialization in Biochemical Engineering TU Dortmund University, Dortmund, Germany |
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| 1999-2003 | Bachelor in Chemical Engineering (B.E) Shivaji University (P.V.P Institute of Technology), Kolhapur, India |
Publications
Peer Reviewed Articles
2016
- Karande R., Schmid A. and Bühler K. (2016)
Applications of multiphasic microreactors for biocatalytic reactions.
Organic Process Research & Development, 20(2):361-370, DOI-Link
- Halan B., Karande R., Bühler K. and Schmid A. (2016)
Catalytic Pseudomonas taiwanensis VLB120ΔC biofilms thrive in a continuous pure styrene generated by multiphasic segmented flow in a capillary microreactor.
Journal of Flow Chemistry, 6(1):39–42, DOI-Link
- Karande R., Debor L., Salamanca D., Bogdahn F., Engesser K.-H., Bühler K. and Schmid A. (2016)
Continuous cyclohexane oxidation to cyclohexanol using a novel cytochrome P450 monooxygenase from Acidovorax sp. CHX100 in recombinant P. taiwanensis VLB120 biofilms.
Biotechnology and Bioengineering, 113(1):52-61, DOI-Link
2015
- Willrodt C., Karande R., Schmid A. and Julsing M. K. (2015)
Guiding efficient microbial synthesis of non-natural chemicals by physicochemical properties of reactants.
Current Opinion in Biotechnology, 35:52-62, DOI-Link
- Salamanca D., Karande R., Schmid A. and Dobslaw D. (2015)
Novel cyclohexane monooxygenase from Acidovorax sp. CHX100.
Applied Microbiology and Biotechnology, 99(16):6889-6897, DOI-Link
2014
- Karande R.*, Halan B.*, Schmid A. and Bühler K. (2014)
Segmented flow is controlling growth of catalytic biofilms in continuous multiphase microreactors.
Biotechnology and Bioengineering, 111(9):1831-1840, DOI-Link
* These authors contributed equally to this work.
2011
- Ruinatscha R., Karande R., Bühler K. and Schmid A. (2011)
Integrated one-pot enrichment and immobilization of styrene monooxygenase (StyA) using Sepabead EC-EA and EC-Q1A anion-exchange carriers.
Molecules, 16(7):5975-5988, DOI-Link
- Karande R., Schmid A. and Bühler K. (2011)
Miniaturizing Biocatalysis: Enzyme catalyzed reactions in an aqueous/organic segmented flow capillary microreactor.
Advanced Synthesis and Catalysis, 353(13):2511-2521, DOI-Link
2010
- Karande R., Schmid A. and Bühler K. (2010)
Enzyme catalysis in an aqueous/organic segment flow microreactor: ways to stabilize enzyme activity.
Langmuir, 26(11):9152-9159, DOI-Link
Patent applications
2011
- Schmid A., Karande R. and Bühler K. (2011)
Segmented Flow Biofilm Reactor.
WO/2012/152337 PCT/EP2011/057724, filed
Oral Presentations
2012
- Karande R., Bühler K. and Schmid A. (2012)
Segmented flow microreactors.
ESBES, 23. - 26. September 2012, Istanbul, Turkey
2011
- Karande R., Bühler K. and Schmid A. (2011)
Segmented flow capillary microreactors: a tool for bio-process intensification.
DECHEMA - Bioverfahrenstechnik an Grenzflächen, 30. - 1.June 2011, Potsdam, Germany
2010
- Karande R., Bühler K. and Schmid A. (2010)
Segment flow capillary microreactors as alternatives to two phase enzymatic batch reactors.
ESBES, 08. - 10. September 2010, Bologna, Italy
2009
- Karande R., Bühler K. and Schmid A. (2009)
Application of segmented flow microsystems to enzymatic catalysis.
Kolloquium der Fakultät BCI, 11.Nov. 2009, Dortmund, Germany
Posters
2015
- Halan B., Karande R., Schmid A. and Bühler K. (2015)
Scale-up and scale-down of truly continous biofilm based bioprocesses.
DECHEMA Himmelfahrtstagung, 11. - 13. May 2015, Hamburg-Bergedorf, Germany
- Halan B., Karande R., Schmid A. and Bühler K. (2015)
Industrial biotechnology for sustainable and energy efficient bioprocesses: miniaturized biofilm based
continuous fine chemical synthesis.
UFZ Energy Days, 24. - 25. February 2015, Leipzig, Germany
2011
- Karande R., Bühler K. and Schmid A. (2011)
Applications of segmented flow microreactors for biocatalysis.
Biotrends, 8. - 9. December 2011, Dortmund, Germany
2010
- Karande R., Bühler K. and Schmid A. (2010)
Asymmetric enzymatic hydrogenation in an aqueous/organic flow capillary microreaktor.
Bioprozessorientiertes Anlagendesign, 10. - 12. Mai 2010, Nürnberg, Germany
2009
- Karande R., Bühler K. and Schmid A. (2009)
Multiphase slug flow microreactor for enzyme based redox biocatalysis.
Dechema, Jahrestagung der Biotechnologen, 8. - 10. September 2009, Mannheim, Germany
2008
- Karande R., Bühler K. and Schmid A. (2008)
Asymmetric Enzymatic Hydrogenation in Capillary Microreactors.
MSB, 9. - 13. March 2008, Berlin, Germany